EVOLUTION AND CONTEMPORARY TREATMENT APPROACH OF SYSTEMIC LUPUSERYTHEMATOSUS. FIRST PATIENT IN BULGARIA ON ANIFROLUMAB THERAPY –A CLINICAL CASE

Abstract

Systemic lupus erythematosus is a chronic autoimmune disease. It can present in subclinical form without organ involvement and with severe organ changes with a variety of clinical symptoms ranging from oral aphthosis to renal failure, pericarditis and pleuritis. It is thought to affect more commonly the female sex, but in the presented clinical case a rare variation of lupus is described in a young 23-year-old man with alopecia and proteinuria, who is also the first patient in Bulgaria on therapy with the interferon 1 blocker anifrolumab.