MEDIASTINOSCOPIC RESECTION OF PRIMARY SMALL CELL CARCINOMAOF THE MEDIASTINUM

Abstract

Small cell carcinoma is a disease mainly of pulmonary origin but in extremely rare cases it can also be observed as a primary mediastinal mass. In the presented case, a 48-year-old man with a clinical manifestation of superior vena cava syndrome and a tumor mass in the upper mediastinum compressing the vessels of the mediastinum is reported. A surgical intervention was performed – videomediastinoscopy with partial excision of the tumor from which primary small cell neuroendocrine carcinoma of the mediastinum was detected during histological and immunohistochemical analysis. Multimodal treatment was carried out and after the surgical intervention the patient was treated with chemotherapy and radiotherapy. It is actively monitored and by the 8th month after diagnosis there is a lack of persistent symptoms. From the monitoring PET/CT scan a minimal single focus with metabolic activity in the mediastinum was observed with significant reduction in tumor size and lack of compression on the mediastinal vessels.