LEOFFLER ENDOCARDITIS – REVIEW

Abstract

Hypereosinophilic syndrome (HES) is a rare condition, which affects a number of organs and systems and the heart is involved in 75% of cases. It is characterized with eosinophilia in blood and myocardium, leading to the development of restrictive cardiomyopathy with endocardial fibrosis in the apical and subvalvular regions of the heart. It can be idiopathic, primary and secondary. The idiopathic HES has two known forms – endomyocardial fybrosis and Leoffler endocarditis. In this publication we will pay attention to Leoffler endocarditis due to the fact that it is necessary to acquire the ability to think about rare diseases, to make a timely diagnosis and start early treatment that would improve the prognosis of these patients.